Methyl Cyanoacetate

Zouping Jinxing Tshuaj Co., Ltd. Yog tias koj yuav mus rau cov lag luam wholesale bulk methyl cyanoacetate hauv Suav teb, txais tos kom tau txais cov qauv dawb los ntawm peb lub hoobkas. Tag nrho cov khoom customized yog nrog cov khoom zoo thiab tus nqi qis.

Cov tsos mob: tsis muaj xim rau daj ntseg daj pob tshab kua; faint aromatic los yog yam ntxwv tsw
Melting point: Kwv yees li . -13 degree
Boiling point: 204-207℃(qhov siab ntawm huab cua); 115℃/ 4.8 kPa (tso siab)
Ceev: 1.122-1.123 g / cm³ (20 degree)
Refractive index: n²⁰_D ≈ 1.417
Flash point: Kaw - khob approx. 110℃( cais raws li cov kua combustible; tsis yog ib qho qis -flash- taw tes nplaim taws)
Solubility: me ntsis soluble hauv dej (kwv yees . 54 g / L ntawm 20 degree); miscible nrog ethanol, diethyl ether, benzene, methanol, thiab lwm yam.
pKa: -hydrogen approx. 2.75- ntau reactive dua li cov esters; vim yog ob lub electron- rho tawm los ntawm -CN thiab -COOMe pawg, pawg methylene nthuav tawm cov kua qaub sib txawv thiab tuaj yeem tsim cov carbanion.

Active methylene chemistry: Undergoes deprotonation nrog lub hauv paus tsis muaj zog (piv txwv li, sodium alkoxides, NaH) thiab koom nrog Knoevenagel condensation (nrog aldehydes / ketones), Michael ntxiv, thiab cyclization (ua heterocycles xws li pyrimidines, thiophenes, thiab pyrazoles).
Cyano pawg transformations: Hydrolysis (yielding cyanoacetic acid los yog malonic acid derivatives); txo ib nrab (rau amides); cov tshuaj tiv thaiv nrog amines (ua cyanoacetamides).
Lub hauv paus rhiab heev: raug rau hydrolysis los ntawm lub hauv paus muaj zog los yog ntev raug rau dej / alkoxides; ceev faj txog qhov siab -kub decomposition tso HCN vim yog pawg –CN.
Cov ntaub ntawv tsis sib xws: Cov tshuaj muaj zog oxidizing, muaj zog acids, acid chlorides, thiab acid anhydrides.

Esterification ntawm cyanoacetic acid nrog methanol (mainstream method): H₂SO₄-catalyzed reflux tom qab neutralization thiab lub tshuab nqus tsev rectification; muab siab yields thiab txoj kev huv.
Cyanation ntawm methyl chloroacetate nrog NaCN: Chloroacetic acid yog thawj esterified rau methyl chloroacetate, ua raws li SN₂ hloov cov tshuaj tiv thaiv nrog sodium cyanide; xav tau kev kho mob ntawm cyanide- muaj cov dej khib nyiab tab sis tuaj yeem siv cov chaw tsim khoom chloroacetic acid uas twb muaj lawm.
Transesterification: Ethyl cyanoacetate + methanol; base-catalyzed pauv cov tshuaj tiv thaiv.

Instant nplaum monomer intermediates: Condensation nrog formaldehyde → poly (methyl 2-cyanoacrylate) → depolymerization kom tawm los methyl -cyanoacrylate (cov ntsiab lus tseem ceeb ntawm "501" nplaum)
Pharmaceutical intermediates: Vitamin B₆, caffeine, buspirone, minoxidil, gabapentin, 2-aminothiophene carboxylates, thiab lwm yam.
Cov tshuaj tua kab nruab nrab: sulfonylurea herbicides, aminopyrimidines; Synthesis ntawm 2,4-diamino-6-hydroxy / chloropyrimidine
Dyes/Pigments: Azo dyes, Solvent Red 196, Cationic Yellow, thiab lwm yam.
Lwm tus: Precursors rau UV absorbers / stabilizers, raw khoom rau malononitrile ntau lawm

Toxicity: Mob toxic; absorbable los ntawm daim tawv nqaij. Qhov ncauj LD₅₀ (guinea npua): 400–800 mg/kg; intraperitoneal LD₅₀ (nas): ≈ 750 mg/kg; dermal LLO (guinea pig): 400 mg/kg.
Irritation: Ua rau mob qhov muag loj (GHS Qhov Muag Irritation Category 2, H319); vapors irritates lub ntsws; kev sib cuag ntawm daim tawv nqaij ua rau mob.
Cyanide-Txoj kev pheej hmoo cuam tshuam: Tsis tso HCN nyob rau hauv ib txwm muaj, tab sis hydrogen cyanide yuav raug tsim los ntawm thermal decomposition los yog cua kub ntev nrog cov acids muaj zog / bases; tswj raws li cov organic cyanide compound.
Kev tiv thaiv: Kaw- cov haujlwm ua haujlwm nrog lub qhov cua hauv zos; siv tshuaj lom neeg- hnab looj tes tiv thaiv, tsom iav kev nyab xeeb, thiab ib nrab- lub ntsej muag ua pa (yog tias muaj ntau tshaj qhov txwv); kom deb ntawm oxidizing tus neeg sawv cev, muaj zog acids, thiab cov hauv paus.
Kev tua hluav taws: Cawv-ua npuas dej, tshuaj qhuav, CO₂, xuab zeb / ntiaj teb; Cov neeg tua hluav taws xav tau kev tiv thaiv kev tiv thaiv thiab tus kheej -cov cuab yeej ua pa (SCBA).
Cia thiab thauj: Khaws rau hauv qhov chaw txias, zoo - qhov cua; khaws nruj nreem kaw thiab tiv thaiv lub teeb (me ntsis teeb-sensitive); khaws cia cais ntawm cov zaub mov thiab lwm yam tshuaj; kov raws li ib tug flammable, kua tshuaj lom; UN 3276 (Class 6.1, Packing Group III).

Cim npe nrov: Tuam Tshoj methyl cyanoacetate manufacturers, lwm tus neeg, Hoobkas