Trifluoroacetic acid

Zouping Jinxing Chemical Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov muag khoom ntawm trifluoroacetic acid hauv Suav teb. Yog tias koj yuav mus rau cov lag luam wholesale bulk trifluoroacetic acid ua nyob rau hauv Suav teb, txais tos kom tau txais cov qauv dawb los ntawm peb lub hoobkas. Tag nrho cov khoom customized yog nrog cov khoom zoo thiab tus nqi qis.

Cov tsos mob: tsis muaj xim, fuming kua nrog pungent vinegar- zoo li tsw (ntau dua li acetic acid); hygroscopic heev.
Kub taw tes: 72.4 degree; Melting point: -15.4 ° C.
Qhov ceev: 1.489 g / cm³ (25 degree).
Flash point: Tsis muaj (tsis yog-flammable, tab sis decomposes ntawm qhov kub thiab txias kom tso cov tshuaj lom neeg xws li phosgene, HF, thiab COF₂).
Acidity: pKa ≈ 0.23; kwv yees li 10⁴ lub sij hawm muaj zog tshaj acetic acid (4.76), nce lub zog ntawm cov inorganic acids muaj zog; cov hluav taws xob muaj zog- rho tawm cov nyhuv ntawm CF₃ pab pawg ua rau carboxyl cov pa roj carbon monoxide muaj kev cuam tshuam rau nucleophilic nres.
Solubility: Miscible nyob rau hauv tag nrho cov proportions nrog dej, methanol, acetonitrile, DCM, thiab DMF; insoluble nyob rau hauv non{0}}polar alkanes.
Cov yam ntxwv tshwj xeeb: Cov kua qaub tsis muaj zog (tuaj yeem raug tshem tawm ntawm cov evaporation rotary nrog rau cov kuab tshuaj); tsis oxidize organic tebchaw (tsis zoo li concentrated sulfuric acid los yog nitric acid).

Peptide cleavage: TFA yog tus qauv cleavage acid nyob rau hauv Boc lub tswv yim (siv nrog scavengers xws li EDT thiab anisole) kom tshem tawm cov peptide los ntawm cov resin yam tsis muaj peptide bonds.
HPLC lub sij hawm txawb: 0.05–0.1% TFA yog siv los kho pH, txo qis silanol kev sib cuam tshuam, thiab ua kom cov duab zoo nkauj (txawm hais tias hnyav ntawm txhua kab thiab tsis sib haum nrog MS, nws tseem yog tus qauv rau thim rov qab-theem HPLC).
Organic synthesis: Catalyzes esterification / acetalization; tshem tawm cov pab pawg Boc (TFA/DCM); ua hauj lwm raws li ib tug proton qhov chaw rau cyclization; siv los qhia cov pab pawg tiv thaiv trifluoroacetyl (–NHCOCF₃).
Proteomics: Nyiam rau cov qauv acidifying tom qab enzymatic digestion; sib haum nrog huab hwm coj spectrometry qauv npaj.
Kev lag luam: Nruab nrab rau fluorinated agrochemicals thiab kws tshuaj; cov ntaub ntawv siv lead ua kua; raw khoom rau trifluoroacetic anhydride (TFAA).

GHS: H314 Ua rau tawv nqaij kub hnyiab thiab qhov muag puas (Qeb 1); H335 Tej zaum yuav ua rau ua pa ua pa; reacts hnyav nrog dej, tso cua sov; decomposes ntawm qhov kub thiab txias kom tso tawm HF thiab phosgene-zoo li tshuaj.
Kev sib cuag ntawm daim tawv nqaij nrog kua → sib sib zog nqus chemical burns (xws li ntxaum ntau dua sulfuric acid vim qhov hnyav molecular); vapor inhalation → hnoos, pulmonary edema.
Kev tuav: Siv lub fume hood; hnav daim npog ntsej muag, hnab looj tes nitrile (tsis txhob siv latex, raws li TFA permeates nws), thiab ib lub tsho tiv no; siv lub pipette rau me me ntim; qhov ncauj pipeting yog nruj me ntsis txwv tsis pub.
Neutralizing spills: Ua ntej nqus nrog xuab zeb / inert khoom, ces maj mam neutralize nrog sodium bicarbonate los yog limewater; Tsis txhob nchuav dej ntau ncaj qha (kev pheej hmoo ntawm kev kub ntxhov thiab txaws).
Cia / Thauj: Siv iav fwj los yog PTFE-kab nruas; kaw nruj nreem kom tsis txhob ya raws ingress; khaws cia nyob rau hauv chav tsev kub (tsis txhob cuam tshuam ntev tshaj 40 degree); cais tawm ntawm cov hauv paus, oxidizing tus neeg sawv cev, thiab amines; Tshuag HF ua ntej- pab tshuaj (calcium gluconate gel) hauv qhov chaw cia.
Kev tua hluav taws: Tsis yog-flammable nws tus kheej, tab sis cov thawv yuav tawg thaum cua sov; siv CO₂ lossis tshuaj tua hluav taws qhuav; Cov neeg tua hluav taws yuav tsum tau ceev faj tiv thaiv HF fumes.

Cim npe nrov: Tuam Tshoj trifluoroacetic acid manufacturers, lwm tus neeg, Hoobkas