Diisopropylethylamine

Diisopropylethylamine

Diisopropylethylamine yog abbreviated li DIPEA (tseem hu ua DIEA lossis i-Pr₂NEt) thiab feem ntau hu ua Hünig lub hauv paus. Nws muaj tus lej CAS 7087-68-5, molecular mis ntawm C₈H₁₉N, thiab molecular hnyav ntawm 129.24. Nws zoo nkaus li tsis muaj xim rau daj ntseg daj pob tshab kua nrog pungent tsw yam ntxwv ntawm amines thiab yog indispensable nyob rau hauv cov organic synthesis.
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Khoom Taw qhia

Zouping Jinxing Chemical Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov muag khoom ntawm diisopropylethylamine hauv Suav teb. Yog tias koj yuav mus rau cov lag luam wholesale bulk diisopropylethylamine ua nyob rau hauv Suav teb, txais tos kom tau txais cov qauv dawb los ntawm peb lub hoobkas. Tag nrho cov khoom customized yog nrog cov khoom zoo thiab tus nqi qis.

 

Cov khoom tseem ceeb physicochemical

 

Cov tsos mob: Cov xim tsis muaj xim rau daj ntseg daj pob tshab kua nrog pungent, amine-zoo li tsw
Kub taw tes: Approx . 126.5–129℃; Melting point: Approx. -46 degree
Qhov ceev: 0.742 g / cm³ (25 degree); Flash point: Kwv yees li . 10-11℃(hnyav heev; GHS qeb 2 flammable kua)
Basicity: Conjugate acid pKa ≈ 10.5–10.9 (piv rau lossis qis dua li triethylamine); Nws tshwm sim los ntawm qhov tseem ceeb steric hindrance thiab tsis tshua muaj nucleophilicity
Solubility: Soluble hauv DCM, THF, cawv, thiab ethers; sparingly soluble hauv dej (kwv yees . 3.9 g / L ntawm 20 degree)

Tej kev siv

 

Khoom -Phase Peptide Synthesis (SPPS): Siv ua ke nrog cov khoom sib txuas xws li HATU, HBTU, lossis DIC los ua kom cov carboxyl pawg thiab ua raws li cov kua qaub, yog li inhibiting amino acid racemization.
Amide / Sulfonamide Condensation: Absorbs HX thaum lub sij hawm cov tshuaj tiv thaiv ntawm acid chlorides los yog sulfonyl chlorides nrog amines, tiv thaiv amine deactivation ntawm protonation.
Mitsunobu, Suzuki, Buchwald–Hartwig, thiab lwm yam.: Ua haujlwm tsis yog -nucleophilic puag lossis co- puag kom ruaj khov rau cov chaw ua haujlwm ntawm cov hlau catalysts.
Pharmaceutical/Agrochemical Intermediates: Ua kom muaj kev xaiv zoo heev ntawm nucleosides, tshuaj tiv thaiv-cov qog nqaij hlav, sulfonylurea tshuaj tua kab, thiab lwm yam.

Kev nyab xeeb, kev cia khoom, thiab kev thauj mus los

 

GHS Cov Lus Qhia Txog Kev Nyab Xeeb: H225 Cov nplaim hluav taws kub heev; H302 Ua phem yog tias nqos; H318 Ua rau qhov muag loj heev; H331 Toxic yog nqus tau; H335 Tej zaum yuav ua rau ua pa ua pa.
Cov vapors hnyav dua li huab cua thiab nws yooj yim mus tsub zuj zuj nyob rau hauv qis -dej thaj chaw, ua rau muaj kev pheej hmoo ntawm flashback; reacts exothermically nrog muaj zog acids, muaj zog oxidizing agents, thiab acyl chlorides.
Kev tuav: Ua haujlwm hauv lub fume hood; siv los tiv thaiv- ntsuas zoo li qub thiab tawg- cov khoom siv hluav taws xob pov thawj; hnav hnab looj tes nitrile thiab looj tsom iav dub. Rau kev nchuav, nqus nrog xuab zeb lossis av; Tsis txhob tso dej ncaj qha nrog dej (amines yaj hauv dej exothermically thiab kis kab mob).
Cia: Khaws kom nruj rau hauv qhov chaw txias (<25°C); store away from ignition sources and oxidizing agents; typically stored in steel drums. Literature suggests avoiding long-term contact with copper or copper-alloy containers.

Cim npe nrov: Tuam Tshoj diisopropylethylamine manufacturers, lwm tus neeg, Hoobkas

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